This is an outline of installing Science Software on a new Mac running Mountain Lion (10.8.x)
Install/upgrade OS
Install XQuartz
Install XCode 4
Install command line tools option from Xcode Preferences Downloads Panel
Install gcc 4.8 and OS X 10.8 compatible gfortran from http://hpc.sourceforge.net (gcc-mlion.tar.gz). This installer installs both gcc and gfortran.
Install pyfits from the StSci site
Download the Scipy Superpack Installer for OSX 10.8 from http://fonnesbeck.github.com/ScipySuperpack/
sudo sh install_superpack.sh
reboot
test install
python
>>> import numpy
>>> import scipy
>>> import pyfits
exit
-- DavidThompson - 12 Aug 2012